After the Second World War, budding film composer Jerry Herst moves to Hollywood to study with infamous master teacher Mario Castelnuovo-Tedesco.

Shaken by the death of his father and discouraged by his stalled career, writer Sal Paradise goes on a road trip hoping for inspiration. While traveling, he is befriended by charismatic and fearless Dean Moriarty and Moriarty's free-spirited and seductive young wife, Marylou. Traveling across the American southwest together, they strive to break from conformity and and search the unknown, and their decisions change the very course of their lives.

Paleontologist Kate Lloyd is invited by Dr. Sandor Halvorson to join his team who have found something extraordinary. Deep below the Arctic ice, they have found an alien spacecraft that has been there for perhaps 100,000 years. Not far from where the craft landed, they find the remains of the occupant. It's cut out of the ice and taken back to their camp but as the ice melts, the creature reanimates and not only begins to attack them but manages to infect them, with team members devolving into...